CRSHs are
groups of homologous microbial proteins likely to have equivalent
biochemical functions.
News(1-1-2011)PrFEcT Target-Selection List (10-15-2010) PrFEcT Target-Selection Committee formed (More details will be available soon)..... (3-31-2010) E. coli Transcriptional Correlation experimental data now available to the public. Sample data can be found from here.Community/Outreach(4-17-2010) Upcoming 1-day mini-symposium on functional elucidation of bacterial proteins...More Info. (4-19-2010 to 4-21-2010) Upcoming poster on CRSH in the 2010 NIGMS Workshop: Enabling Technologies in Structure and Function...More Info CollaboratorsNortheast Structural Genomics Consortium (NESG) Protein Function Elucidation Team (PrFEct) Protein Structure Initiative (PSI)
To analyze/nominate CRSHs for protein purification and structure determination, please use the online tool.
An example output of the target analysis/nomniation process can be found in here.
To perform gene-context analysis on combinations of related CRSHs,
select the "MegaCRSH" tab at the top of this page.
Search for the CRSHs by the name . Input either the Consensus Name, the Product Name, or the
Keyword in the search field (for example, 'SecA' or
'translocase').
Predicted Interaction Search
Go directly to
the CRSH summary page using the CRSH ID number.
CRSH ID Search
Sequence
homology search vs. CRSH profile (slow -- can take several
minutes).
Please input the sequence in FASTA format.
Sequence Homology
Sequence
homology search vs. all bacterial protein sequences (faster, but
could still take > 1 minute).
Please input the sequence in FASTA format.
